The Metigen War is in full swing as Alex and Caleb approach Seneca. Caleb initiates an Intelligence Division protection protocol, and he and Alex join Director Delavasi at a safe house as several actions are set in motion.

Alex contacts Dr. Canivon to discuss the feasibility of enriching human/Artificial connections, only to discover Sagan is already under attack by the Metigens. The Alliance is defending the independent colony, and Alex asks her mother to ensure Canivon and her Artificial, Valkyrie, are rescued and brought to Earth. Caleb reaches out to Isabela, who divulges the truth about their father’s profession and his death. Caleb confronts Graham about it, and a heated argument ensues.

On Earth, Kennedy works with the Alliance to manufacture the material the Siyane’s hull transformed into, now called ‘adiamene.’ She implores Noah to seek the help of his estranged father, a metals expert. Noah agrees, but the request introduces tension into their relationship. Devon tries to restore communications to Fionava and NW Command, while elsewhere at EASC Devon’s boss, Brigadier Hervé, is contacted by Hyperion, the same alien Marcus Aguirre was in league with.

Alex, Caleb, Miriam, Richard and Graham converge on a secluded, private estate on Pandora, and Alex and Miriam reunite in a more tender encounter than either were expecting. Alex reveals the full extent of her plan to the others, including that she intends to spearhead it by being the first to neurally link to an Artificial. Even as they meet, agents of the Metigens seek to stop them—the safe house on Seneca is blown up, and the assassin Matei Uttara pursues them to Pandora.

When Miriam breaks the news to Alex that her former lover, Ethan Tollis, died in an explosion, she flees to grieve in private. Caleb goes after her, but it intercepted by Uttara. A bloody fight ensues, during which both men are gravely injured. Alex arrives on the scene and shoots Uttara in the head, killing him. Caleb collapses from his injuries.

Noah meets with his father, Lionel, in a combative encounter. Despite the tension between them, Lionel agrees to help with the adiamene production, and they travel to Berlin to meet Kennedy at the manufacturing facility. Once Lionel begins work, Noah confronts Kennedy about her motives for forcing a reunion with his father, but the matter isn’t resolved.

Caleb regains consciousness, and he and Alex share an emotional moment in which they both come to realizations about each other and the strength of their relationship. Miriam learns Liam has attacked the Federation colonies of New Cairo and Ogham with nuclear weapons, and she is forced to travel to Seneca to smooth things over with Federation leadership. Once Caleb is healed enough to travel, he and Alex depart for Earth. On the way, he contacts Mia and asks her to come to Earth, though he can’t yet tell her why.

Miriam meets with Field Marshal Gianno and Chairman Vranas, and in a surprising move tells them she won’t take any active steps to stop Liam until after the Metigens are defeated, as they must concentrate all their efforts on the alien invasion. She then tells Gianno about Alex’s plan. Gianno selects the fighter pilot, Morgan Lekkas, for participation, and recalls her from Elathan, where Morgan was helping to defend against a Metigen attack.

Alex and Caleb reach EASC Headquarters, where they are reunited with Kennedy and Noah. Alex meets with Dr. Canivon, who was safely evacuated off Sagan, and informs the woman she wants to use Valkyrie as her Artificial partner in the project they’ve dubbed ‘Noetica.’ While monitoring the war effort, EASC’s Artificial, Annie, discovers her programming has been corrupted and suspects Hervé of tampering.

Miriam returns to Earth and meets with Prime Minister Brennon. She tells him they are losing the war—they and the Federation are suffering too many losses and will run out of ships and soldiers long before the Metigens do—then pitches Noetica to him.

Mia arrives in Vancouver. Alex and Caleb ask her to be a part of Noetica, together with her Artificial, Meno, and she agrees. With time running out and the Metigens advancing, Noetica is approved and Devon Reynolds and Annie are selected as the last participants.

Alex is the first to undergo the procedure Dr. Canivon has devised to allow a linking between an Artificial’s quantum processes and a human mind at a neural level. Caleb and Miriam each contend with fear and worry about her well-being, and Miriam comes to recognize how much Caleb cares for Alex.

Alex awakens to her and Valkyrie’s thoughts clashing and overrunning one another. She struggles to regain control of her mind and deal with the flood of information, and with Caleb’s help is able to do so. She informs her mother the Metigens are deviating from their pattern and heading for Seneca and Romane in massive force.

While the others undergo the procedure, Alex and Miriam meet with Brennon, Gianno and Vranas. Alex makes the case that the Metigens are coming for Seneca and Romane, and Miriam and Brennon decide to send the EA fleet to defend the two worlds.

On Liam’s cruiser, the Akagi, Captain Brooklyn Harper begins a mutinous campaign to stop Liam. She enlists one of her teammates, Kone, and a comm officer, who slips a message out to Col. Malcolm Jenner saying Liam’s next target is Krysk and asking for intervention. Then she and Kone sabotage the remaining nukes on the Akagi.

Malcolm is defending Scythia from the Metigens when he receives Harper’s message. He passes it on to Miriam, who informs Gianno. Gianno claims she can’t spare the ships to defend the colony if the Metigens are almost at Seneca.

Caleb is furious the military won’t defend Krysk, where his sister and niece live, and makes the gut-wrenching decision to try to rescue them. Alex gives him the Siyane, saying it’s his only chance to reach Krysk in time. After a tearful parting, Caleb leaves, but not before recruiting Noah to go with him.

Alex, Devon, Mia and Morgan, and their Artificial counterparts, Valkyrie, Annie, Meno and Stanley, gather to strategize. They name themselves “Prevos,” taken from the Russian word for “The Transcended,” and begin to realize the extent of their new capabilities. Alex shares a touching goodbye with her mother before leaving with the fleet for Seneca.

Devon remains at EASC, where he and Annie will oversee all fronts of the war, and comes to terms with the fact Hervé is working for the Metigens. At the same time, Hyperion confronts Hervé about Noetica. Because she wants the Metigens defeated, Hervé does not reveal to Hyperion that she has secretly placed a ‘kill switch’ in the Prevos’ firmware, which when used will sever their connections to the Artificials—and also likely kill them.

Graham, Vranas and Gianno discuss the coming attack and express concerns over Noetica. When Graham returns to his office, Will Sutton—Richard’s husband and a Senecan intelligence agent—is waiting on him and bears mysterious news.